Dr. Dennis Van Hoof was diagnosed with Type 1 Diabetes (T1D) at the turn of the millennium, so he has had an intimate relationship with this disease for nearly 2 decades. In spite of the physical and mental setback, he refused to let T1D to stop him from realizing his dreams. The disease demanded that he adopted a more structured and organized lifestyle to prevent both dangerous hypoglycemic events and long-term complications as a result of poor diabetes management. What it gave him in return was a new lifestyle that allowed him to achieve goals that he would never have pursued without diabetes. The lifestyle improvements that he made turned into sustainable habits that still allow him to do and eat whatever he wants. Over time, he started to realize that his lifestyle to manage diabetes had become an inspiration™ for people around him as he journeyed to success.
Dr. Dennis Van Hoof currently also works as a trained Lifestyle Coach on the YMCA’s Diabetes Prevention Program, which uses a Centers for Disease Control and Prevention (CDC)-approved curriculum as part of the CDC-led National Diabetes Prevention Program.
With this program, pre-diabetics and those at risk are introduced to topics that encourage them to explore how healthy eating, physical activity, behavior changes and weight loss can help them reduce their risk of developing diabetes. This is done in a supportive, small-group environment where participants meet frequently for a total of 25 times over 1 year.
Before that, he worked for 5 years as a research scientist at the Diabetes Center of the University of California San Francisco (UCSF).
At the Utrecht University in The Netherlands (Europe), he followed a Bachelor’s program in general biology and then acquired his Master’s degree in molecular and cellular biology.
After that, he completed the PhD track to obtain his Doctor’s degree in biochemical physiology by studying the LDL-cholesterol metabolic processes for people with hypercholesterolemia.
He became a Certified Life Coach (CLC) through successful completion of the training provided by the Life Purpose Institute (LPI).
Before he migrated to the USA, he worked as an academic post-doctoral fellow at the Hubrecht Institute in collaboration with the Utrecht University, where he investigated the development of heart muscle cells for treatment of myocardial infarction.
He moved to the USA for an academic research project on the insulin-producing pancreatic beta cells at the UCSF with funding from the California Institute for Regenerative Medicine (CIRM) and the Juvenile Diabetes Research Foundation (JDRF).
He switched from academia to industry by joining a small startup company, ARMO Biosciences, to develop products that activate the immune system so that it attacks tumors in cancer patients.
He continued his career as a manager at BD Biosciences, supervising the R&D activities to commercialize diagnostic platforms for the blood cancers leukemia and lymphoma, which frequently manifest in children.
Check out his LinkedIn profile.
As of today, he has a track record of 30 scientific articles and publications (26 of these are listed in PubMed), and has given numerous seminars at multiple international conferences all over the world.
Diabetes-related scientific research articles and book chapters:
- “Phosphorylation of NEUROG3 links endocrine differentiation to the cell cycle in pancreatic progenitors” by Dennis van Hoof, Nicole A.J. Krentz, Zhongmei Li, Akie Watanabe, Mei Tang, Cuilan Nian, Michael S. German, Francis C. Lynn – Dev Cell (2017) 41: 129-142.e6
- “Directed differentiation of human pluripotent stem cells along the pancreatic endocrine lineage” by Dennis Van Hoof, Mulye E. Liku – Book chapter in: Springer, Chapter 10 “Pluripotent Stem Cells: Methods and Protocols” (2013) 997: 127-140
- “Differentiation of human embryonic stem cells into pancreatic endoderm in patterned size-controlled clusters” by Dennis Van Hoof, Adam D. Mendelsohn, Rina Seerke, Tejal A. Desai, Michael S. German – Stem Cell Research (2011) 6: 276-285
- “Derivation of insulin-producing cells from human embryonic stem cells” by Dennis Van Hoof, Kevin A. D’Amour, Michael S. German – Stem Cell Research (2009) 3: 73-87
He has dedicated much of his time to diabetes education and talks to the local community as well as volunteering and fund-raising events, such as the American Diabetes Association (ADA) “Tour de Cure” and the Juvenile Diabetes Research Foundation (JDRF) “Walk to Cure.”